MO07. Novel Immunotherapeutic Strategies in mNSCLC

Room 104, Grand Ballroom, 1F
Live Stream
Metastatic Non-small Cell Lung Cancer - Immunotherapy

Information

⏬Presentation Slides will be accessible below within 24 hours after the session concludes⏬

Track: Metastatic Non-small Cell Lung Cancer - Immunotherapy

This session presents six abstracts in NSCLC immunotherapy, organized into two thematic parts covering both established combinations and emerging novel agents. The first part features three studies on immune checkpoint inhibitor-based strategies, including the Lonestar trial of nivolumab/ipilimumab with local consolidation, gotistobart in the post-PD-(L)1 setting, and 8-year follow-up data from KEYNOTE-189/407, followed by an expert discussion. The second part highlights three novel immunotherapeutic platforms: an EGFR CAR T-cell therapy for HER2-mutant NSCLC, an anti-PD-1-proIL-2 fusion protein, and a PD-L1/4-1BB bispecific antibody combined with chemotherapy. Together, these presentations capture the evolving NSCLC immunotherapy landscape, from refining checkpoint inhibitor combinations to advancing next-generation engineered therapies.

Date
Monday, September 14, 2026 (KST)
Session Type
Mini Oral
CME
Not for CME Credit

Presentation(s) in this Session

Chair

Monday, September 14, 2026 5:00 PM to 5:01 PM

Chair

Monday, September 14, 2026 5:01 PM to 5:02 PM

MO07.01. Development of a Shared Neoantigen Peptide Library to Promote Personalized Vaccine Strategy in Patients With Non-Small Cell Lung Cancer

Monday, September 14, 2026 5:02 PM to 5:07 PM

MO07.02. Characteristics and Outcomes to Immunotherapy in Patients With NSCLC Harboring Class II and III BRAF Alterations

Monday, September 14, 2026 5:07 PM to 5:12 PM

MO07.03. Biallelic Inactivation of KEAP1/STK11 Predicts Benefit to Dual PD-(l)1/CTLA4 Immune Checkpoint Blockade in Non-Small Cell Lung Cancers

Monday, September 14, 2026 5:12 PM to 5:17 PM

Q&A

Monday, September 14, 2026 5:17 PM to 5:25 PM

MO07.04. Gotistobart vs Docetaxel in Metastatic Squamous NSCLC After PD-(l)1 Progression: Updated Overall Survival of the stage 1 of PRESERVE-003

Monday, September 14, 2026 5:25 PM to 5:30 PM

MO07.05. Phase 2 Study of Investigational Agents Plus Tislelizumab ± Chemotherapy in Untreated Locally Advanced/Metastatic NSCLC

Monday, September 14, 2026 5:30 PM to 5:35 PM

MO07.06. Phase II Study of Opamtistomig (LBL-024), a PD-L1/4-1BB Bispecific Antibody Plus Chemotherapy in First-Line Advanced NSCLC

Monday, September 14, 2026 5:35 PM to 5:40 PM

Q&A

Monday, September 14, 2026 5:40 PM to 5:48 PM

MO07.07. First-in-Human Study of HC010, a Novel PD-1/VEGF/CTLA-4 Trispecific Antibody: Preliminary Results

Monday, September 14, 2026 5:48 PM to 5:53 PM

MO07.09. Peripheral Blood PD-1+ Tfh Cells Predict Response and Survival to PD-1 Blockade in Lung Adenocarcinoma

Monday, September 14, 2026 5:58 PM to 6:03 PM

MO07.10. Updated Efficacy Results of Rilvegostomig for Checkpoint Inhibitor (CPI)-NaïVe Metastatic Non-Small-Cell Lung Cancer (Mnsclc)

Monday, September 14, 2026 6:03 PM to 6:08 PM

Q&A

Monday, September 14, 2026 6:08 PM to 6:20 PM

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